Nurse practitioner and physician assistant jobs in Spartanburg, SC

Each job shows the pay its employer posts; too few here post an hourly rate for a typical range. NPs & PAs pay across South Carolina is measured from more jobs.

By open jobs on this board: Spartanburg Regional Healthcare System (6), Pediatrix Medical Group (2) and Curana Health (1).

1 of the open nurse practitioner and physician assistant jobs here says so in its own posting: Psychiatric Mental Health Nurse Practitioner (PMHNP) - sign on bonus at iTrust Wellness Group (up to $7,500 sign-on bonus).

1 of the open nurse practitioner and physician assistant jobs here says so in its own posting: Psychiatric Mental Health Nurse Practitioner (PMHNP) - sign on bonus at iTrust Wellness Group (...January 1 , giving employees a paid week-long winter holiday break. Relocation assistance available for...).

By their own postings here, a sign-on bonus: iTrust Wellness Group (up to $7,500). The employers compared.

Spartanburg Medical Center: 2 of 5 stars, 81% of patients said nurses always communicated well (Medicare, Jul 2026). Each one opens its employer's other hospitals and jobs. Patients' ratings of their care, not employees' of the jobs.

Spartanburg Regional Home Health: 3.5 of 5 stars, 86% of patients said the team communicated well (Medicare, Sep 2026). Each one opens its employer's other agencies and jobs. Patients' ratings of their care, not employees' of the jobs.

Spartanburg Regional Med Ctr Hospice: 85% of families said the team always communicated well (4 stars), in Medicare's hospice survey. Each one opens its employer's other hospices and jobs. Families' ratings of the care, not employees' of the jobs.

By what they reported to OSHA for 2025, in work injuries and illnesses per 100 full-time workers: Apella - Spartanburg Medical Center AHM (Spartanburg Regional Healthcare System) 4.4, against 5.1 at general hospitals nationwide; Spartanburg Medical Center (Spartanburg Regional Healthcare System) 3.3, best estimate 3.4, against 5.1 at general hospitals nationwide; Medical Group of the Carolinas (Spartanburg Regional Healthcare System) 0.3, best estimate 0.4, against 3.6 at physicians' offices nationwide; Apella - Medical Group of the Carolinas AHM (Spartanburg Regional Healthcare System) 2.0, best estimate 2.1, against 3.6 at physicians' offices nationwide. These are the employers' own reports. Workplace injuries in South Carolina.

A state NP (APRN) license with national board certification, or PA-C certification and a state PA license. Each posting lists its own requirements.