Nurse practitioner and physician assistant jobs in Irvine, CA
15 open nurse practitioner and physician assistant jobs in Irvine, California, at 6 employers. Diagnose, treat and prescribe as an advanced practice provider in clinics, hospitals and urgent care.
Newest nurse practitioner and physician assistant jobs in Irvine
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Weatherby HealthcareLocum tenens agency
A locum tenens agency placing physicians, NPs and PAs in assignments across the US.

Wapiti Medical StaffingLocum tenens agency
Places physicians and advanced practice providers in locum tenens assignments, often in rural communities.
These agencies and apps pay CareJobs.Now a referral fee when someone we introduce is placed or signs up. It costs you nothing and never changes your pay. Hospital and clinic jobs below keep their own order.

PA or NP (RNFA), Gynecologic Oncology Surgery (full-time)
MemorialCare · Irvine, CA· today


Certified Registered Nurse Anesthetist (CRNA), Orange County/Anaheim (Full Time)
Kaiser Permanente · Anaheim and Irvine, CA· 1d ago
$131.45–$143.63/hr
Physician Assistant or Nurse Practitioner - Urology and Urogynecology
City of Hope California · Irvine, CA· 2w ago
$119,000–$213,000/yr
Physician Assistant - Inpatient Surgical Oncology Rounding
City of Hope California · Irvine, CA· 4w ago

Physician Assistant II / NP II - Thoracic Surgery, Part-time (Irvine)
Kaiser Permanente · Irvine, CA· 4w ago
$94.72–$116.29/hr
Nurse Practitioner - GI Medical Oncology
City of Hope California · Irvine and Duarte, CA· 1mo ago

DOCS Health · Santa Rosa, Stockton and 10 more, CA· 1mo ago

DOCS Health · Santa Rosa, Stockton and 7 more, CA· 1mo ago

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NPs & PAs occupations in Irvine
Each opens the town's jobs in that occupation.
Nurse practitioner and physician assistant jobs near Irvine
Towns within thirty-five miles with a page for this kind of job, nearest first.
Nurse practitioner and physician assistant jobs in Irvine, CA: common questions
What do nurse practitioner and physician assistant jobs in Irvine, CA pay?
Each job shows the pay its employer posts; too few here post an hourly rate for a typical range. NPs & PAs pay across California is measured from more jobs.
Who has the most nurse practitioner and physician assistant jobs in Irvine, CA?
By open jobs on this board: City of Hope California (8), DOCS Health (2) and Kaiser Permanente (2).
What do you need to get hired?
A state NP (APRN) license with national board certification, or PA-C certification and a state PA license. Each posting lists its own requirements.
Sources and method
Cite this page
CareJobs.Now. (2026). Nurse practitioner and physician assistant jobs in Irvine, CA. Data as of October 21, 2026. https://carejobs.now/states/california/irvine/nurse-practitioners