Healthcare jobs in O'Fallon, IL
Nurse practitioner and physician assistant jobs in O'Fallon, IL
10 open nurse practitioner and physician assistant jobs in O'Fallon, Illinois, at 5 employers. Diagnose, treat and prescribe as an advanced practice provider in clinics, hospitals and urgent care.
Newest nurse practitioner and physician assistant jobs in O'Fallon
Checked 9 Nov 2026, 07:49 UTC
$79/hr
$79/hr
$128,153/yr


$170/hr
Selected agencies hiring now
All agencies and apps →
Cross Country HealthcareTravel nursing agency
A national staffing company placing travel nurses, allied professionals, therapists and locum tenens providers, with local and per diem work too.
Places: Nurses, NPs & PAs, Doctors, CNAs & PCTs

GHR HealthcareHealthcare staffing agency
Places nurses, allied health, advanced practice providers, physicians, revenue cycle and healthcare IT staff through temporary, travel and direct hire roles in all 50 states.
Places: Nurses, NPs & PAs, Doctors, Allied health
These agencies and apps pay CareJobs.Now a referral fee when someone we introduce is placed or signs up. It costs you nothing and never changes your pay. Hospital and clinic jobs below keep their own order.
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NPs & PAs occupations in O'Fallon
Each opens the town's jobs in that occupation.
What nurse practitioner and physician assistant jobs in O'Fallon offer
Counted from each job's own posting, the same reading as the lists across the state.
Relocation help: 3 jobs
- Advanced Practice Registered Nurse (APRN) / Physician Assistant (PA) - Gastroenterology at Hospital Sisters Health System...and patient outcome/patient satisfaction bonuses Sign on bonus and relocation assistance both available...
- Advanced Practice Registered Nurse (APRN) / Physician Assistant (PA) - Pain Management at Hospital Sisters Health System...patient outcome/patient satisfaction bonuses Sign-on bonus available Relocation assistance available To...
- Physician Assistant / Nurse Practitioner General Cardiology at Hospital Sisters Health System...and patient outcome/patient satisfaction bonuses Sign-on bonus and relocation assistance both available....
Nurse practitioner and physician assistant jobs near O'Fallon
Towns within thirty-five miles with a page for this kind of job, nearest first.
Nurse practitioner and physician assistant jobs in O'Fallon, IL: common questions
What do nurse practitioner and physician assistant jobs in O'Fallon, IL pay?
Each job shows the pay its employer posts; too few here post an hourly rate for a typical range. NPs & PAs pay across Illinois is measured from more jobs.
Who has the most nurse practitioner and physician assistant jobs in O'Fallon, IL?
By open jobs on this board: Hospital Sisters Health System (3), North American Partners in Anesthesia (3) and Proactive MD (2).
Which nurse practitioner and physician assistant jobs in O'Fallon, IL offer relocation assistance?
3 of the open nurse practitioner and physician assistant jobs here say so in their own posting: Advanced Practice Registered Nurse (APRN) / Physician Assistant (PA) - Gastroenterology at Hospital Sisters Health System (...and patient outcome/patient satisfaction bonuses Sign on bonus and relocation assistance both available...); Advanced Practice Registered Nurse (APRN) / Physician Assistant (PA) - Pain Management at Hospital Sisters Health System (...patient outcome/patient satisfaction bonuses Sign-on bonus available Relocation assistance available To...); Physician Assistant / Nurse Practitioner General Cardiology at Hospital Sisters Health System (...and patient outcome/patient satisfaction bonuses Sign-on bonus and relocation assistance both available....).
Which employers hiring nurse practitioner and physician assistant jobs in O'Fallon, IL offer a sign-on bonus, a shift differential or tuition help?
By their own postings here, tuition or student loan help: Hospital Sisters Health System (tuition help up to $5,250 a year). The employers compared.
What do you need to get hired?
A state NP (APRN) license with national board certification, or PA-C certification and a state PA license. Each posting lists its own requirements.
Sources and method
- CareJobs.Now job board: open jobs in O'Fallon, IL, read every night from each employer's own careers site, published 9 Nov 2026
- BLS OEWS May 2025: St. Louis, MO-IL metropolitan area, published 15 May 2026
- US Census Bureau, 2024 Gazetteer Files (places)
Cite this page
CareJobs.Now. (2026). Nurse practitioner and physician assistant jobs in O'Fallon, IL. Data as of 9 Nov 2026. https://carejobs.now/states/illinois/ofallon/nurse-practitioners