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Clinical Nurse IV - Clinic (Surgery)

  • BLS
  • RN license
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About the job

Join the transformative team at City of Hope , where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. City of Hope’s growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and treatment facilities in Atlanta, Chicago and Phoenix. Our dedicated and compassionate employees are driven by a common mission: To deliver the cures of tomorrow to the people who need them today.

City of Hope in Upland is seeking an experienced and highly skilled Clinical Nurse IV to join our outpatient surgical oncology team. In this advanced nursing role, you will provide clinical leadership and expertise in managing complex patient needs, including clinical triage, postoperative concerns, symptom escalation, patient education, and care coordination.

The Clinical Nurse IV will manage in-basket messages and non-emergent patient calls, using advanced clinical judgment and critical thinking to assess patient needs, determine appropriate interventions, and coordinate timely follow-up. This role also serves as a key clinical resource to the nursing team and collaborates closely with physicians, advanced practice providers, and the nurse manager to support safe, high-quality, patient-centered care.

The ideal candidate brings strong clinical expertise in oncology and surgical care, excellent communication and organizational skills, and the ability to effectively prioritize and manage multiple complex patient needs in a fast-paced outpatient environment. The Clinical Nurse IV will play an important role in supporting patients throughout their treatment journey while serving as a trusted clinical resource for the care team.

As a successful candidate, you will

  • Strong knowledge of oncology nursing principles and treatment modalities.
  • Experience caring for complex oncology patients in an outpatient setting
  • Ability to recognize and escalate urgent/emergent conditions appropriately
  • Solid understanding of treatment plans and supportive care needs
  • Strong understanding of postoperative care and potential complications
  • Ability to recognize changes in patient condition and identify when symptoms require escalation
  • Strong care coordination and follow-through skills
  • Ability to collaborate effectively with physicians, APPs, nurses, and other members of the multidisciplinary team
  • Ability to coordinate referrals, follow-up appointments, testing, and other patient needs
  • Strong understanding of continuity of care across the outpatient settng
  • Ability to mentor or guide less experienced nurses
  • Strong organizational and time-management skills
  • Commitment to patient-centered care and quality outcomes
  • Proficiency with EMR systems (in-basket management)
  • Familiarity with outpatient clinic workflows
  • Understanding of regulatory and compliance standards
  • Schedule: Monday – Friday 745am – 4:15pm

Your qualifications should include

  • Bachelor’s degree or master’s degree in nursing is required.
  • Current California RN license.
  • Minimum of three (3) years related experience, preferred background in oncology nursing.
  • Basic Life Support (BLS) CPR Card through American Heart Association
  • ONS Chemotherapy/ Biotherapy Certificate or Chemotherapy/ Immunotherapy Certificate (Must be obtained within 6 months of hire)
  • Current National certification must be maintained to retain CN IV status (effective February 22, 2022).
  • COH (Nursing Excellence Department and HR) maintain a list of approved certifications which is a subset of ANCC Magnet-recognized certifications as updated in ANCC Demographic Data Collection Tool® (DDCT).
  • Excellent communication and interpersonal skills, with a caring and empathetic demeanor.
  • Ability to work collaboratively in a fast-paced clinical setting.

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.

To learn more about our Comprehensive Benefits, please CLICK HERE .

Please note : City of Hope is committed to a safe and transparent hiring experience. Please be aware that scammers may attempt to impersonate our organization through fake job postings, emails or interviews.

  • Apply only through our official website or trusted partner platforms.
  • City of Hope will never request payment or fees at any stage of the hiring process.
  • We will not request sensitive personal or financial information prior to the acceptance of a formal offer.
  • All communications will come from official @coh.org email addresses.
  • Interviews are conducted only through approved, professional channels.
  • Be cautious of unsolicited communications, urgent requests or opportunities that seem inconsistent with standard hiring practices.
  • If you receive any suspicious communication, please report it to careers@coh.org .

From City of Hope California's job posting, checked Oct 21, 2026. The employer's own page is the final word on requirements and availability.

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About City of Hope California

City of Hope California hires nurses, pharmacy staff and advanced practice providers in Duarte, Irvine and other towns in California.

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