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Nurses

Clinical Nurse II - Hematology

  • BLS
  • RN license
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About the job

Join the transformative team at City of Hope , where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. City of Hope’s growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and treatment facilities in Atlanta, Chicago and Phoenix. Our dedicated and compassionate employees are driven by a common mission: To deliver the cures of tomorrow to the people who need them today.

The Hematology Unit delivers specialized, comprehensive care to patients with blood-related cancers, including leukemia, lymphoma, and multiple myeloma. The unit also has expertise in caring for patients receiving CAR T-cell therapy and those enrolled in clinical research trials. Using a multidisciplinary approach, the team diagnoses, treats, and manages a wide range of hematologic malignancies.

We are seeking dedicated, knowledgeable nurses who demonstrate strong critical-thinking skills, sound clinical judgment, and a compassionate approach to patient care. Excellent communication, thorough documentation, and the ability to incorporate cultural, psychosocial, and spiritual considerations into care planning are essential to success in this role.

Key Responsibilities include

Patient Assessment and Monitoring:

Conduct comprehensive assessments for patients with hematologic malignancies, including physical evaluations, medical history reviews, and symptom assessments such as fatigue, bruising, or bleeding. Monitor vital signs, laboratory values, and treatment responses to promptly identify changes in condition.

Chemotherapy Administration:

Safely administer chemotherapy and other systemic therapies in accordance with established protocols. Verify accurate dosing, monitor for adverse reactions, and provide supportive interventions to reduce treatment-related complications.

Symptom Management:

Assess and manage symptoms related to both disease and treatment, including pain, nausea, anemia, and neutropenia. Administer medications, implement comfort measures, and educate patients on self-management strategies to enhance comfort and quality of life.

Patient and Family Education:

Provide clear education to patients and families regarding diagnoses, treatment plans, expected side effects, and symptom management. Offer guidance on medication adherence and connect patients with supportive resources such as nutrition services, counseling, and financial assistance.

Care Coordination

Work collaboratively with the interdisciplinary care team to create and carry our individualized care plans. Coordinate diagnostic testing, appointments, and specialty consultations to ensure continuity of care across the treatment journey.

Hours: Full time Nights - 12-shift (7:00pm - 7:30am)

Your qualifications should include

  • Bachelor’s Degree or Master’s degree in Nursing is required
  • Current California RN license
  • Minimum of 1-3 years related experience
  • Basic Life Support (BLS) CPR Card through American Heart Association
  • Chemotherapy/ Biotherapy Certificate or Chemotherapy/ Immunotherapy Certificate (Must be obtained within 6 months of hire)

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.

To learn more about our Comprehensive Benefits, please CLICK HERE .

From City of Hope California's job posting, checked Oct 21, 2026. The employer's own page is the final word on requirements and availability.

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About City of Hope California

City of Hope California hires nurses, pharmacy staff and advanced practice providers in Duarte, Irvine and other towns in California.

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